DNA detection on lateral flow test strips: enhanced signal sensitivity using LNA-conjugated gold nanoparticles.

نویسندگان

  • Shiva K Rastogi
  • CharLene M Gibson
  • Josh R Branen
  • D Eric Aston
  • A Larry Branen
  • Patrick J Hrdlicka
چکیده

A lateral flow test strip assay, enabling sensitive detection of DNA specific to the foodborne pathogen E. coli O157:H7, is described. The use of LNA-conjugated gold nanoparticle probes, along with signal amplification protocols, results in minimum detectable concentrations of ~0.4 nM.

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عنوان ژورنال:
  • Chemical communications

دوره 48 62  شماره 

صفحات  -

تاریخ انتشار 2012